Meditrol hCG Pregnancy Test
Meditrol hCG Pregnancy Test from medichem
For rapid detection of the pregnancy hormone hCG in urine. This test delivers a visual, qualitative result and was developed for professional use.
- hCG urine rapid test
- highly sensitive (20 mU/ml)
- easy to use
- Meditrol’s hCG pregnancy test is used successfully above all in physicians’ practices
- hCG can be detected seven days after conception already with this test
- detailed information and exact instructions for use
Human choriongonadotropin (hCG) is a glycoprotein hormone that the placenta begins to build shortly after conception. In the course of a normal pregnancy, hCG can be verified in serum by day seven after conception (1-4). The hCG concentration climbs very rapidly, often reaching a value of 100 mIU/mL by the first missed period (2-5) and finally peaks in the 10th to 12th week of pregnancy in the 30,000 – 100,000 mIU/mL range.
The early appearance of hCG after conception and the subsequent increased concentration in early pregnancy make it the ideally suited indicator for detecting pregnancy early on. However, an elevated urine hCG level comparable to the one in early pregnancy can also appear in conjunction with a cystic mole or a choriocarcinoma, so that these possibilities need to be excluded before diagnosing a pregancy.
The hCG strip test is a rapid membrane test for detecting hCG starting with a concentration of 20 mIU/mL in urine. The test employs monoclonal antibodies to evidence hCG in urine. The immune reaction’s specificity excludes a cross-reaction with the structurally-related glycoprotein hormones FSH, LH and TSH when present in physiological concentrations.
The hCG strip test is a chromatographic immunoassay test for the rapid, qualitative detection of hCG in urine samples. The membrane’s test area has bound to it antibodies against the hCG’s a-chain and the control area has on it goat anti-mouse antibodies. As the test starts, the sample is mixed with colloidal gold particles that carry monoclonal antibodies against the hCG b-chain on their surfaces. Next, capillary action transports all particles along with the fluid across the membrane. If the result is positive, that is, if there is hCG, an antibody-hCG antibody-gold aggregate builds and with it a colored band appears in the test area. If no colored band appears in this area, it is a negative test. In either case, there should be a colored band visible in the control region, signifying that the test was conducted successfully.
This article is excluded from withdrawal.
Micro Albumin from medichem
The meditrol Microalbumin-test is an immuno-chemical lateral flow test. It serves for the semi-quantitative proof of small amounts of albumin in urine. The color intensity of the test result-line continuously decreases at a concentration-range of 20 mg/L – 100 mg/L, so the amount of albumin can be read on a color scale. Albumin concentrations above these values are apparent through complete disappearance of the test result-line.
The meditrol Microalbumin-test is designated exclusively for professional use and is evaluated visually.
The product serves for first screening of urine samples and delivers an initial analytical result, because fluctuations in the urine concentration are not considered. Positive test results above 20 mg/L should therefore be ensured through a more specific quantitative method. Clinical observations and a professional verdict should influence the interpretation of every albumin-test, especially in the case of an initial positive test result. The meditrol micro albumin-test is a competitive immunoassay, in which the immobilized human albumin of the test competes for a limited number of antibody binding-sites with albumin potentially contained in the urine.
The test strip is coated with human albumin in the test-line region (T-Region). A pillow with color-coded anti-albumin antibodies is at the starting end of the membrane. The antibodies enter the T-region with the added urine, which flows along the membrane through capillary force. If no albumin is present in the urine, the antibodies adhere to the immobilized albumin on the membrane, so that a red-tinted line appears. But if albumin is present in the urine, if competes for the binding sites of the antibody with the albumin in the T-region. The bond of the antibodies in the T-region is increasingly inhibited with increasing albumin-concentration in the urine, and the color intensity of the test result-line becomes continually weaker. This decrease in color intensity can be observed with the included color-scale, with whose help the color-intensity of a specific albumin concentration can be assigned (semi-quantitative evaluation). If the test result-line disappears completely, it means that the albumin concentration is above the area suited for semi-quantitative evaluation. The test result then should be categorized as positive.
- to determine albumin concentration
- storable at room temperature
- indication from 20 mg/l
This article is excluded from withdrawal.